Cost-effectiveness of Multigene Testing for All Patients With Breast Cancer
This cost-effectiveness microsimulation modeling study estimates incremental lifetime effects, costs, and cost-effectiveness of multigene testing of all patients with breast cancer compared with...
View ArticleA Single-Arm, Phase 2 Trial of Combined Bevacizumab and Nivolumab in Relapsed...
This phase 2 clinical trial examines the use of nivolumab combined with bevacizumab in treatment of women with relapsed platinum-sensitive or platinum-resistant ovarian cancer.
View ArticleAspirin Use and All-Cause and Cancer Mortality Risk Among Older Adults
This cohort study uses data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screen Trial to examine the associations among regular aspirin use, obesity, and all-cause and cancer mortality among...
View ArticleUse of Powder in the Genital Area and Ovarian Cancer Risk
Women have used powders for genital hygiene for decades to absorb odor and moisture. While rates of powder use in the genital area have declined over the last 50 years, it remains a routine practice...
View ArticleAssociation of Powder Use in the Genital Area With Risk of Ovarian Cancer
This cohort study uses pooled data from 4 cohorts to estimate associations between perineal use of body powder and ovarian cancer in US women.
View ArticleProgression-Free Survival as a Surrogate End Point of Overall Survival in...
This systematic review and meta-analysis evaluates whether progression-free survival is a validated surrogate end point for overall survival in patients with advanced ovarian cancer.
View ArticleAssociation Between Genetically Proxied Inhibition of HMG-CoA Reductase and...
This study uses mendelian randomization to estimate the associations between genetic variants related to reduced HMG-CoA reductase activity and epithelial ovarian cancer in the general population and...
View ArticleGermline Variant Status and Therapy Response in High-risk Early-Stage Breast...
This secondary analysis of a randomized clinical trial assesses treatment outcomes in women with different biological types of breast cancer according to germline variant status of BRCA1/2 and...
View ArticleAssociation Between Breastfeeding and Ovarian Cancer Risk
This pooled analysis analyzes the association between breastfeeding (ie, ever/never, duration, timing) and ovarian cancer risk overall and by histotype.
View ArticleLaparoscopic Surgery and Rupture Risk for Women With Ovarian Cancer
This cohort study examines the association between the use of minimally invasive surgery, capsule rupture, and survival among women with stage I epithelial ovarian cancer.
View ArticleDetection of TP53 Clonal Variants in Papanicolaou Test Samples Before HGS-EOC...
This cohort study assesses whether TP53 clonal variants can be detected in Papanicolaou test samples from women later diagnosed with high-grade serous epithelial ovarian cancer (HGS-EOC).
View ArticleAssociation of a Polygenic Risk Score With Breast Cancer Among Women Carriers...
This case-control study examines the association of polygenic risk scores with changes in breast cancer risk in women who are carriers of pathogenic variants in breast cancer susceptibility genes.
View ArticleCytoreductive Surgery With or Without HIPEC for Stage III Epithelial Ovarian...
This cohort study compares survival outcomes between primary cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) vs primary cytoreductive surgery alone for patients with stage...
View ArticleTreatment and Survival Among Women With Advanced-Stage Epithelial Ovarian Cancer
This cohort study compares time trends in the use of neoadjuvant chemotherapy and survival rates among women with advanced-stage epithelial ovarian cancer.
View ArticleTrends in Positive BRCA Test Results Among Older Women in the US
This cross-sectional study assesses whether the rate of positive BRCA test results changed between 2008 and 2018 among older women in the United States.
View ArticlePembrolizumab With Bevacizumab and Oral Metronomic Cyclophosphamide for...
This single-arm, phase 2 nonrandomized clinical trial assesses the efficacy and safety of combined pembrolizumab, bevacizumab, and oral metronomic cyclophosphamide in women with recurrent...
View ArticleCost-effectiveness of Maintenance Therapy Following Treatment of Primary...
This economic evaluation evaluated the cost-effectiveness of maintenance strategies for patients with (1) a BRCA variant, (2) homologous recombination deficiency without a BRCA variant, or (3)...
View ArticleAssociation of Radiotherapy for Rectal Cancer and Second Gynecological...
This cohort study assesses the association between radiotherapy and the risk of individual types of second gynecological malignant neoplasms in patients with rectal cancer and estimates survival...
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